BDBM50537058 CHEMBL4531719

SMILES CCCCc1cn(nn1)-c1ccc(NC(=O)Nc2ccccc2C)cc1

InChI Key InChIKey=LZPQWTRWEKFHPZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50537058   

TargetATP-dependent RNA helicase DDX1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50537058(CHEMBL4531719)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human DDX1 helicase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase DDX3X(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50537058(CHEMBL4531719)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human DDX3X ATPase activity using DDX3 as substrate by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase DDX3X(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50537058(CHEMBL4531719)
Affinity DataIC50:  300nMAssay Description:Inhibition of recombinant DDX3X (unknown origin) helicase activity using dsRNA as substrate incubated for 40 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetATP-dependent RNA helicase DDX3X(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50537058(CHEMBL4531719)
Affinity DataIC50:  300nMAssay Description:Inhibition of human DDX3X using dsRNA as substrate measured every 30 sec for 40 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase DDX3X(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50537058(CHEMBL4531719)
Affinity DataIC50:  300nMAssay Description:Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed