BDBM50537907 CHEMBL4636390

SMILES [H][C@]12CN([C@@H](Cc3ccccc3)CN1C(=O)[C@]1([H])[C@H](c3c(cc4OCOc4c3OC)[C@]21[H])c1ccccc1)C(C)=O

InChI Key InChIKey=VTOITEGQWZFNRK-NCPBTPGXSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50537907   

TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50537907(CHEMBL4636390)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of P-glycoprotein overexpressed in human SW620/AD300 cells assessed as reversal of doxorubicin resistance by measuring doxorubicin IC50 at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50537907(CHEMBL4636390)
Affinity DataIC50:  1.10E+3nMAssay Description:Reversal of P-gp mediated multidrug resistance in human SW620/AD300 cells assessed as potentiation of doxorubicin-induced antiproliferative activity ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed