BDBM50537994 CHEMBL4640845

SMILES Cc1cc(C)c(Cc2cc(OCCNC(=O)C=C)c3cc([nH]c3c2)-c2n[nH]c3cc(ccc23)C(F)F)c(C)c1

InChI Key InChIKey=SLMHJYKHTHZBPT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50537994   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50537994(CHEMBL4640845)
Affinity DataIC50:  445nMAssay Description:Inhibition of BTK (unknown origin) using TK as substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50537994(CHEMBL4640845)
Affinity DataIC50:  62nMAssay Description:Inhibition of ITK (unknown origin) using TK as substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed