BDBM50538312 CHEMBL4641726
SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CC1(C)\C(=C/C=C/C=C/C2=[N+](CCCCS([O-])(=O)=O)c3ccccc3C2(C)C)N(CCCCCC(=O)NCCN2CCN(CCCCC3CCN(CC(=O)N4c5ccccc5NC(=O)c5ccccc45)CC3)CC2)c2ccc(cc12)S(O)(=O)=O
InChI Key InChIKey=VOPGEUVVFSVDCS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50538312
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of Regensburg
Curated by ChEMBL
University Of Regensburg
Curated by ChEMBL
Affinity DataKi: 0.525nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 receptor stably expressed in CHO-K9 cells by radioligand competitive binding assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
University Of Regensburg
Curated by ChEMBL
University Of Regensburg
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]-NMS from human muscarinic M4 receptor stably expressed in CHO-K9 cells by radioligand competitive binding assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Regensburg
Curated by ChEMBL
University Of Regensburg
Curated by ChEMBL
Affinity DataKi: 2.90nMAssay Description:Displacement of [3H]-NMS from human muscarinic M1 receptor stably expressed in CHO-K9 cells by radioligand competitive binding assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University Of Regensburg
Curated by ChEMBL
University Of Regensburg
Curated by ChEMBL
Affinity DataKi: 81nMAssay Description:Displacement of [3H]-NMS from human muscarinic M3 receptor stably expressed in CHO-K9 cells by radioligand competitive binding assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
University Of Regensburg
Curated by ChEMBL
University Of Regensburg
Curated by ChEMBL
Affinity DataKi: 135nMAssay Description:Displacement of [3H]-NMS from human muscarinic M5 receptor stably expressed in CHO-K9 cells by radioligand competitive binding assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
University Of Regensburg
Curated by ChEMBL
University Of Regensburg
Curated by ChEMBL
Affinity DataKd: 9.5nMAssay Description:Binding affinity to human muscarinic M4 receptor expressed in CHO-K9 cells incubated in dark at 22 degree C for 2 hrs by FACSCalibur flow cytometric ...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of Regensburg
Curated by ChEMBL
University Of Regensburg
Curated by ChEMBL
Affinity DataKd: 4.70nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells incubated in dark measured after 60 mins by Hoechst H33342 dye based confo...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of Regensburg
Curated by ChEMBL
University Of Regensburg
Curated by ChEMBL
Affinity DataKd: 0.480nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells at 22 +/- 1 degree C preincubated for 180 mins followed by atropine additi...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of Regensburg
Curated by ChEMBL
University Of Regensburg
Curated by ChEMBL
Affinity DataKd: 0.891nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells incubated in dark at 22 degree C for 2 hrs by FACSCalibur flow cytometric ...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of Regensburg
Curated by ChEMBL
University Of Regensburg
Curated by ChEMBL
Affinity DataKd: 0.891nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells incubated in dark at 22 degree C for 2 hrs by FACSCalibur flow cytometric ...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Regensburg
Curated by ChEMBL
University Of Regensburg
Curated by ChEMBL
Affinity DataKd: 6.5nMAssay Description:Binding affinity to human muscarinic M1 receptor expressed in CHO-K9 cells incubated in dark at 22 degree C for 2 hrs by FACSCalibur flow cytometric ...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of Regensburg
Curated by ChEMBL
University Of Regensburg
Curated by ChEMBL
Affinity DataKd: 4.68nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells incubated in dark measured after 60 mins by Hoechst H33342 dye based confo...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of Regensburg
Curated by ChEMBL
University Of Regensburg
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Antagonist activity at human muscarinic M2 receptor expressed in HEK293 cells co-expressing HA-Galphaq/i5 assessed as inhibition of carbachol-induced...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of Regensburg
Curated by ChEMBL
University Of Regensburg
Curated by ChEMBL
Affinity DataIC50: 224nMAssay Description:Antagonist activity at human muscarinic M2 receptor expressed in HEK293 cells co-expressing HA-Galphaq/i5 assessed as inhibition of carbachol-induced...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
University Of Regensburg
Curated by ChEMBL
University Of Regensburg
Curated by ChEMBL
Affinity DataIC50: 102nMAssay Description:Antagonist activity at human muscarinic M4 receptor expressed in HEK293 cells co-expressing HA-Galphaq/i5 assessed as inhibition of carbachol-induced...More data for this Ligand-Target Pair