BDBM50538510 CHEMBL4640989
SMILES COc1ccc(cc1OC)-c1cnn2c(N)c(-c3ccccc3)c(OC3CCNCC3)nc12
InChI Key InChIKey=QZKXRJMVQTZACR-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50538510
TargetKinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
The Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of KIF5B-RET (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-l...More data for this Ligand-Target Pair
TargetCoiled-coil domain-containing protein 6(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
The Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of CCDC6/RET (unknown origin) transfected in human LC2/ad cells assessed as reduction in cell viability incubated for 6 days by CellTiter ...More data for this Ligand-Target Pair
TargetTranscription factor ETV6/Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
The Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of TEL/KDR (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-luc...More data for this Ligand-Target Pair