BDBM50538684 CHEBI:40035::CHEMBL1230309

SMILES Cc1c[nH]cn1

InChI Key InChIKey=XLSZMDLNRCVEIJ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 8 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50538684   

TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL

LigandBDBM50538684(CHEBI:40035 | CHEMBL1230309)Copy SMILESCopy InChI

Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of recombinant human QC using H-Gln-AMC hydrobromide as fluorogenic substrate incubated for 6 hrs by fluorometric microplate reader analys...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDB

In DepthDetails PubMed
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TargetPeptidyl-prolyl cis-trans isomerase FKBP5(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL

LigandBDBM50538684(CHEBI:40035 | CHEMBL1230309)Copy SMILESCopy InChI

Affinity DataKd:  2.90E+6nMAssay Description:Binding affinity to 15N-labeled FKBP51 (1 to 140 residues) (unknown origin) expressed in Escherichia coli OD2N by two-dimensional 1H/15N HSQC NMR spe...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDB

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI