BDBM50538926 CHEMBL4638416

SMILES Cl.CCN1CCc2cc(ccc2C1=O)-c1c(C)nc2c(OCc3ccccc3)cccn12

InChI Key InChIKey=PYVPWCOTBDSZAO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50538926   

TargetPresenilin-1(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50538926(CHEMBL4638416)
Affinity DataIC50: >5.00E+4nMAssay Description:Modulatory activity of gamma secretase in human SKNBE2 cells assessed as decrease in Abeta42 levels incubated for 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed