BDBM50539906 CHEMBL4648005::US11142507, Compound MFH-3-35-1

SMILES CC(C)(C)c1cnc(CSc2cnc(NC3CCCC(C3)Nc3ccc(NC(=O)C=C)cc3)s2)o1

InChI Key InChIKey=KHUWOOWXQFGVBZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50539906   

TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50539906(CHEMBL4648005 | US11142507, Compound MFH-3-35-1)
Affinity DataIC50:  30.9nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50539906(CHEMBL4648005 | US11142507, Compound MFH-3-35-1)
Affinity DataIC50:  15.7nMAssay Description:Jurkat cells were treated with DMSO or concentration of compound indicated. 6 hours after treatment, cells were washed and harvested by resuspending ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50539906(CHEMBL4648005 | US11142507, Compound MFH-3-35-1)
Affinity DataIC50:  557nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent