BDBM50540020 CHEMBL4642454

SMILES CS(=O)(=O)c1ncn2c(NCc3c4CCOc4ccc3F)ncc(C3CCS(=O)(=O)CC3)c12

InChI Key InChIKey=PXXCTVCAYXWEMB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50540020   

TargetPolycomb protein EED(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50540020(CHEMBL4642454)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of EED ( 1 to 441 residues) (unknown origin) pre-incubated for 15 mins before biotin-H3K27me3 (19 to 33 residues) addition and further inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed