BDBM50540167 CHEMBL4642463

SMILES [H][C@]1(C[C@H]1C(=O)NCCCC)[C@]12COC[C@@]1([H])CSC(N)=N2

InChI Key InChIKey=WVAFMFLAAGBATC-OXIWPEFWSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50540167   

TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540167(CHEMBL4642463)
Affinity DataIC50:  6.64E+3nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCathepsin D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540167(CHEMBL4642463)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540167(CHEMBL4642463)
Affinity DataIC50:  7.33E+3nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed