BDBM50540803 CHEMBL4633299
SMILES Cc1cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c(C)n1-c1cccc(NC(=O)CCCCCCC(=O)NO)c1
InChI Key InChIKey=HQAHZUWVVKNTRB-UHFFFAOYSA-N
Data 16 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50540803
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant HDAC8 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Menoufia University
Curated by ChEMBL
Menoufia University
Curated by ChEMBL
Affinity DataIC50: 7.37E+3nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibition of human recombinant HDAC5 using AMC-K(TFA)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.68E+4nMAssay Description:Inhibition of human recombinant HDAC4 using AMC-K(TFA)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant HDAC3 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of human recombinant HDAC2 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibition of human recombinant HDAC1 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Menoufia University
Curated by ChEMBL
Menoufia University
Curated by ChEMBL
Affinity DataIC50: 7.37E+3nMAssay Description:Inhibition of human EZH2 using core histone as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.68E+4nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibition of HDAC5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant HDAC6 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair