BDBM50541858 CHEMBL4645901

SMILES CNC(=O)c1csc(n1)[C@@H]1C[C@@H](CN1C(=O)c1ccc(cc1)-c1nn[nH]n1)NC(=O)[C@@H]1CC(=O)N(C)C(=O)N1

InChI Key InChIKey=SYFLGRBSBZONAM-DZKIICNBSA-N

Data  1 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50541858   

TargetN-alpha-acetyltransferase 50(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50541858(CHEMBL4645901)
Affinity DataIC50:  7nMAssay Description:Inhibition of wild type human Naa50 (1852 to 2082 residues) expressed in Escherichia coli BL21(DE3) cells using MLGPEGGEGK peptide as substrate after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-alpha-acetyltransferase 50(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50541858(CHEMBL4645901)
Affinity DataKd:  105nMAssay Description:Binding affinity to full length human N-terminal His-tagged/GST-tagged Naa50 expressed in Escherichia coli BL21(DE3) cells in by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-alpha-acetyltransferase 50(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50541858(CHEMBL4645901)
Affinity DataKd:  32nMAssay Description:Binding affinity to full length human N-terminal His-tagged/GST-tagged Naa50 expressed in Escherichia coli BL21(DE3) cells in presence of CoA by SPR ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-alpha-acetyltransferase 50(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50541858(CHEMBL4645901)
Affinity DataKd:  27nMAssay Description:Binding affinity to full length human N-terminal His-tagged/GST-tagged Naa50 expressed in Escherichia coli BL21(DE3) cells in presence of acetyl CoA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed