BDBM50541938 CHEMBL4640857
SMILES Nc1nc(n[nH]1)N1CCC(CC1)N1Cc2ccccc2OC[C@@H]1Cc1ccc(Cl)cc1
InChI Key InChIKey=TYNJYIOCKJBQLY-FQEVSTJZSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50541938
Affinity DataIC50: 7nMAssay Description:Inhibition of full length recombinant C-terminal His-tagged human acidic mammalian chitinase expressed in CHOK1 cells assessed as reduction in chitin...More data for this Ligand-Target Pair
Affinity DataIC50: 915nMAssay Description:Inhibition of full length recombinant C-terminal His-taged human CHIT1 expressed in CHOK1 cells assessed as reduction in chitinolytic activity using ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Oncoarendi Therapeutics
Curated by ChEMBL
Oncoarendi Therapeutics
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Displacement of Tracer Red from human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Oncoarendi Therapeutics
Curated by ChEMBL
Oncoarendi Therapeutics
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by automated Qpatch-clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Oncoarendi Therapeutics
Curated by ChEMBL
Oncoarendi Therapeutics
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of tracer red binding to human ERG expressed in HEK293 cell membranes measured after 2 to 6 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 137nMAssay Description:Inhibition of recombinant full-length C-terminal his-tagged mouse CHIT1 expressed in CHO-K1 cells assessed as reduction in chitinolytic activity usin...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of full-length C-terminal his-tagged human AMCase expressed in CHO-K1 cells assessed as reduction in chitinolytic activity using 4-methylu...More data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of full-length C-terminal his-tagged mouse AMCase expressed in expressed in CHO-K1 cells assessed as reduction in chitinolytic activity us...More data for this Ligand-Target Pair
Affinity DataIC50: 915nMAssay Description:Inhibition of full-length C-terminal his-tagged human recombinant CHIT1 catalytic domain (1 to 386 residues) expressed in HEK293F cells assessed as r...More data for this Ligand-Target Pair