BDBM50541950 CHEMBL4643001

SMILES CN1C[C@H](Cc2ccc(Cl)cc2)N(Cc2cc(Cl)ccc12)C1CCN(CC1)c1n[nH]c(N)n1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50541950   

TargetAcidic mammalian chitinase(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50541950(CHEMBL4643001)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of full length recombinant C-terminal His-tagged human acidic mammalian chitinase expressed in CHOK1 cells assessed as reduction in chitin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50541950(CHEMBL4643001)
Affinity DataIC50:  800nMAssay Description:Displacement of Tracer Red from human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChitotriosidase-1(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50541950(CHEMBL4643001)
Affinity DataIC50:  420nMAssay Description:Inhibition of full length recombinant C-terminal His-taged human CHIT1 expressed in CHOK1 cells assessed as reduction in chitinolytic activity using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed