BDBM50543279 CHEMBL4641916

SMILES OC(=O)C(F)(F)F.[O-]C(=O)C(F)(F)F.CN(C)c1ccc(\C=C\C=C\c2cc(C)[n+](CCCCNc3c(NCCCOc4cccc(CN5CCCCC5)c4)c(=O)c3=O)c(C)c2)cc1

InChI Key InChIKey=NKXKKEVFDGFYIA-UHFFFAOYSA-N

Data  1 KI  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50543279   

TargetHistamine H2 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50543279(CHEMBL4641916)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in baculovirus infected Sf9 cells incubated for 60 mins by scintillation count...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50543279(CHEMBL4641916)
Affinity DataKd:  74nMAssay Description:Binding affinity to human H2R expressed in human HEK293T cells incubated for 60 mins by automated cell imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50543279(CHEMBL4641916)
Affinity DataKd:  87nMAssay Description:Binding affinity to human H2R expressed in human HEK293T cells incubated for 60 mins by imaging flow cytometry analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50543279(CHEMBL4641916)
Affinity DataKd:  28nMAssay Description:Binding affinity to human H2R expressed in human HEK293T cells incubated for 90 mins by flowcytometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed