BDBM50544833 PSMA-617::Vipivotide tetraxetan

SMILES OC(=O)CC[C@H](NC(=O)N[C@@H](CCCCNC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)[C@H]1CC[C@H](CNC(=O)CN2CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC2)CC1)C(O)=O)C(O)=O

InChI Key InChIKey=JBHPLHATEXGMQR-LFWIOBPJSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50544833   

TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50544833(PSMA-617 | Vipivotide tetraxetan)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to PSMA in human LNCaP cells after 45 mins in presence of 68Ga-labeled PSMA-10 by gamma counting assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50544833(PSMA-617 | Vipivotide tetraxetan)
Affinity DataIC50:  11nMAssay Description:Displacement of [125I]MIP-1095 from PSMA in human PC3-PIP cells after 1 hr by gamma counter analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed