BDBM50545314 CHEMBL4643397

SMILES Nc1nc(NCCN2CCN(CC2)c2ccc(cc2)S(N)(=O)=O)nc2sc(nc12)-c1ccco1

InChI Key InChIKey=DBSSNIVKOMKZGN-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50545314   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50545314(CHEMBL4643397)
Affinity DataKi:  86nMAssay Description:Displacement of [3H]ZM241383 from human A2AR expressed in CHO cells by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50545314(CHEMBL4643397)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]DPCPX from human A1 receptor expressed in CHO cells by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50545314(CHEMBL4643397)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]AB-MEGA from human A3R expressed in CHO cells by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50545314(CHEMBL4643397)
Affinity DataIC50:  0.340nMAssay Description:Inverse agonist activity at human A2B receptor expressed in CHO cells assessed as reduction in cAMP levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50545314(CHEMBL4643397)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human A2B receptor expressed in CHO cells assessed as reduction in cAMP productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed