BDBM50545548 CHEMBL4633247
SMILES [H][C@@]12Cc3c([nH]c4cc(OC)ccc34)[C@H](CC(C)C)N1C(=O)[C@H](CCOC(=O)C(C)(C)C)NC2=O
InChI Key InChIKey=VUVJUQNDSAIPOG-JBACZVJFSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50545548
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Reversal of human ABCG2-mediated multidrug resistance in HEK293/R482 cells assessed as effect on mitoxantrone-induced cytotoxicity by measuring mitox...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Reversal of human ABCG2-mediated multidrug resistance in HEK293/R482 cells assessed as effect on topotecan-induced cytotoxicity by measuring topoteca...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance in human H460-MX20 cells assessed as effect on topotecan-induced cytotoxicity by mea...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance in human S1-M1-80 cells assessed as effect on topotecan-induced cytotoxicity by meas...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance in human H460-MX20 cells assessed as effect on mitoxantrone-induced cytotoxicity by ...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance in human S1-M1-80 cells assessed as effect on mitoxantrone-induced cytotoxicity by m...More data for this Ligand-Target Pair