BDBM50545654 CHEMBL4633223

SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@]5(Cc1cc(cnc21)-c1cccc(C)c1)OCCCc1ccccc1)ccc3O

InChI Key InChIKey=MHDRQXQQWMEREP-QJMCPCMJSA-N

Data  3 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50545654   

TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50545654(CHEMBL4633223)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by competition radioligand bin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50545654(CHEMBL4633223)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]-diprenorphine from human mu opioid receptor expressed in CHO cell membranes incubated for 1 hr by competition radioligand bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50545654(CHEMBL4633223)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]-diprenorphine from human delta opioid receptor expressed in CHO cell membranes incubated for 1 hr by competition radioligand bin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50545654(CHEMBL4633223)
Affinity DataIC50: <0.169nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cell membranes assessed as reduction in SNC80-induced [35S]GTPgammaS binding prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50545654(CHEMBL4633223)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed