BDBM50547882 CHEMBL4753100::US11377438, Example 15
SMILES Cc1nc(N2CCC(F)(F)CC2)c(cc1C1CCC1)C(=O)Nc1ccnc(c1)S(N)(=O)=O
InChI Key InChIKey=OFPKYCQAWZHRGU-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50547882
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 6.5nMAssay Description:The following buffers were used for the QubeŽ recordings: External buffer for Nav1.8 QubeŽ recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 1...More data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human Nav1.8 expressed in HEK293 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair