BDBM50547895 CHEMBL4751356::US11377438, Example 177
SMILES NS(=O)(=O)c1cc(NC(=O)c2cc(OC(F)(F)F)cnc2N2CCCC(F)(F)CC2)ccn1
InChI Key InChIKey=HSWWXBFOMGQCFB-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50547895
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 2.80nMAssay Description:The following buffers were used for the QubeŽ recordings: External buffer for Nav1.8 QubeŽ recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 1...More data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human Nav1.8 expressed in HEK293 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair