BDBM50548117 CHEMBL4776026

SMILES CNC(=O)c1cnc2cc(OC)c(OC)cc2c1Nc1ccccc1CCS(C)(=O)=O

InChI Key InChIKey=NZMCFAREIXJKAF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50548117   

TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50548117(CHEMBL4776026)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed