BDBM50548393 CHEMBL3716446

SMILES O=c1nc(OCC2COCCO2)cc2-c3ccc(CCc4ccccn4)cc3CCn12

InChI Key InChIKey=CMMVXNAUFZNASV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50548393   

TargetG-protein coupled receptor 84(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50548393(CHEMBL3716446)
Affinity DataIC50:  8nMAssay Description:Antagonist activity at recombinant human GPR84 stably overexpressed in HEK293T cell membranes co-expressing G-alpha assessed as inhibition of DIM-sti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Mus musculus)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50548393(CHEMBL3716446)
Affinity DataIC50:  39nMAssay Description:Inverse agonist activity at recombinant mouse GPR84 receptor expressed in HEK293 cells co-expressing GNAO1 transcription variant 1 assessed as reduct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50548393(CHEMBL3716446)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at recombinant human GPR84 receptor expressed in HEK293 cells co-expressing GNAO1 transcription variant 1 assessed as reduction i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed