BDBM50549374 CHEMBL4746374

SMILES C[C@@H](OCc1ccccc1)[C@H](NC(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)c1cccc(c1)-c1cccnc1)C#N

InChI Key InChIKey=PHUPMBKAOHPRFE-ZDERHKTGSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50549374   

TargetProcathepsin L(Homo sapiens (Human))
University Of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50549374(CHEMBL4746374)
Affinity DataKi:  1nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University Of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50549374(CHEMBL4746374)
Affinity DataKi:  5nMAssay Description:Inhibition of human cathepsin B using Z-Phe-Arg-AMC fluorogenic peptide as substrate preincubated for 2 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
University Of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50549374(CHEMBL4746374)
Affinity DataKi:  13nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
University Of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50549374(CHEMBL4746374)
Affinity DataKi: <1.00E+4nMAssay Description:Inhibition of recombinant human cathepsin K using Z-Leu-Arg-AMC as substrate measured after 20 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University Of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50549374(CHEMBL4746374)
Affinity DataIC50:  9nMAssay Description:Inhibition of human cathepsin B at pH 6 using Z-Phe-Arg-AMC fluorogenic peptide as substrate preincubated for 2 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University Of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50549374(CHEMBL4746374)
Affinity DataIC50:  33nMAssay Description:Inhibition of human cathepsin B at pH 4.5 using Z-Phe-Arg-AMC fluorogenic peptide as substrate preincubated for 2 mins followed by substrate addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed