BDBM50549374 CHEMBL4746374
SMILES C[C@@H](OCc1ccccc1)[C@H](NC(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)c1cccc(c1)-c1cccnc1)C#N
InChI Key InChIKey=PHUPMBKAOHPRFE-ZDERHKTGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50549374
Affinity DataKi: 1nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of human cathepsin B using Z-Phe-Arg-AMC fluorogenic peptide as substrate preincubated for 2 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Inhibition of recombinant human cathepsin K using Z-Leu-Arg-AMC as substrate measured after 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human cathepsin B at pH 6 using Z-Phe-Arg-AMC fluorogenic peptide as substrate preincubated for 2 mins followed by substrate addition a...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of human cathepsin B at pH 4.5 using Z-Phe-Arg-AMC fluorogenic peptide as substrate preincubated for 2 mins followed by substrate addition...More data for this Ligand-Target Pair