BDBM50549700 CHEMBL4740126

SMILES OC(=O)c1cc(ncn1)-c1ccc(Cl)c(OC2CC2)c1

InChI Key InChIKey=SIYCDJHEVASOGW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50549700   

TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549700(CHEMBL4740126)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of KMO (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Mus musculus)
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549700(CHEMBL4740126)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549700(CHEMBL4740126)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed