BDBM50550091 CHEMBL4648477
SMILES NC(=N)c1ccc(Nc2ccc(cc2)-c2cc3ccc(cc3[nH]2)C(N)=N)cc1
InChI Key InChIKey=TZRXNWCLKYWDNH-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50550091
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of recombinant human His-tagged PRMT1 expressed in Escherichia coli BL21 (DE3) using biotin-labeled histone H4-20 as substrate incubated f...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of recombinant human His-tagged PRMT3 expressed in Escherichia coli BL21 (DE3) using biotin-labeled SMD1 as substrate incubated for 10 min...More data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Georgia
Curated by ChEMBL
University Of Georgia
Curated by ChEMBL
Affinity DataIC50: 2.76E+4nMAssay Description:Inhibition of recombinant GST-tagged CARM1 (unknown origin) expressed in Escherichia coli using histone H3.3 peptide as substrate incubated for 120 m...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University Of Georgia
Curated by ChEMBL
University Of Georgia
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of recombinant His-tagged human G9a expressed in Escherichia coli BL21 (DE3) using biotin-labeled histone H3-20 peptide as substrate incub...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Georgia
Curated by ChEMBL
University Of Georgia
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of PRMT6 (unknown origin) using biotin-labeled SMD1 as substrate incubated for 30 mins in presence of [3H]-SAM cofactor by scintillation p...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 7(Homo sapiens (Human))
University Of Georgia
Curated by ChEMBL
University Of Georgia
Curated by ChEMBL
Affinity DataIC50: 2.36E+4nMAssay Description:Inhibition of recombinant GST-tagged PRMT7 (unknown origin) expressed in Escherichia coli using biotin-labeled SMD1 as substrate incubated for 120 mi...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 8(Homo sapiens (Human))
University Of Georgia
Curated by ChEMBL
University Of Georgia
Curated by ChEMBL
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of recombinant His-tagged human PRMT8 expressed in Escherichia coli BL21 (DE3) using biotin-labeled histone H4-20 peptide as substrate inc...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Georgia
Curated by ChEMBL
University Of Georgia
Curated by ChEMBL
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of PRMT5/MEP50 (unknown origin) using biotin-labeled histone H4-20 peptide as substrate incubated for 8 mins in presence of [3H]-SAM cofac...More data for this Ligand-Target Pair