BDBM50550092 CHEMBL4740128

SMILES CNC(=N)N\N=C(\C)c1ccc2oc3ccc(cc3c2c1)C(\C)=N\NC(=N)NC

InChI Key InChIKey=GDRFOQDJRLEMDH-UIXGLJBASA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50550092   

TargetProtein arginine N-methyltransferase 1(Homo sapiens)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50550092(CHEMBL4740128)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of recombinant human His-tagged PRMT1 expressed in Escherichia coli BL21 (DE3) using biotin-labeled histone H4-20 as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50550092(CHEMBL4740128)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of recombinant human His-tagged PRMT3 expressed in Escherichia coli BL21 (DE3) using biotin-labeled SMD1 as substrate incubated for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50550092(CHEMBL4740128)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibition of recombinant GST-tagged CARM1 (unknown origin) expressed in Escherichia coli using histone H3.3 peptide as substrate incubated for 120 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50550092(CHEMBL4740128)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of recombinant His-tagged human G9a expressed in Escherichia coli BL21 (DE3) using biotin-labeled histone H3-20 peptide as substrate incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50550092(CHEMBL4740128)
Affinity DataIC50:  6.01E+3nMAssay Description:Inhibition of PRMT6 (unknown origin) using biotin-labeled SMD1 as substrate incubated for 30 mins in presence of [3H]-SAM cofactor by scintillation p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 7(Homo sapiens (Human))
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50550092(CHEMBL4740128)
Affinity DataIC50:  2.33E+4nMAssay Description:Inhibition of recombinant GST-tagged PRMT7 (unknown origin) expressed in Escherichia coli using biotin-labeled SMD1 as substrate incubated for 120 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 8(Homo sapiens (Human))
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50550092(CHEMBL4740128)
Affinity DataIC50:  1.76E+4nMAssay Description:Inhibition of recombinant His-tagged human PRMT8 expressed in Escherichia coli BL21 (DE3) using biotin-labeled histone H4-20 peptide as substrate inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50550092(CHEMBL4740128)
Affinity DataIC50:  1.89E+4nMAssay Description:Inhibition of PRMT5/MEP50 (unknown origin) using biotin-labeled histone H4-20 peptide as substrate incubated for 8 mins in presence of [3H]-SAM cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed