BDBM50550229 CHEMBL4755679

SMILES COc1ccc2[nH]cc(CCNC(=O)CN(CCCCCCCCNc3c4CCCCc4nc4ccc(OC)cc34)C(=O)CCCC[C@@H]3CCSS3)c2c1

InChI Key InChIKey=PWDRAIJCBVSHCO-UUWRZZSWSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50550229   

TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universit£

Curated by ChEMBL
LigandPNGBDBM50550229(CHEMBL4755679)
Affinity DataIC50:  15nMAssay Description:Inhibition of Electrophorus electricus AChE pre-incubated for 10 mins before addition of acetylthiocholine iodide substrate and further incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50550229(CHEMBL4755679)
Affinity DataIC50:  1.73E+3nMAssay Description:Inhibition of BuChE in human erythrocyte hemo-lyzates pre-incubated for 5 mins before addition of butyrylthiocholine iodide substrate by Ellman's met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50550229(CHEMBL4755679)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of AChE in human erythrocyte hemo-lyzates pre-incubated for 5 mins before addition of acetylthiocholine iodide substrate by Ellman's metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50550229(CHEMBL4755679)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of horse serum BuChE pre-incubated for 10 mins before addition of butyrylthiocholine iodide substrate and further incubated for 15 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed