BDBM50550658 CHEMBL4792191
SMILES Oc1ccc2Sc3c(Cc2c1)cccc3-c1cc(=O)cc(o1)N1CCOCC1
InChI Key InChIKey=GIFQPYLTHILYRR-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50550658
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Chdi Management/Chdi Foundation
Curated by ChEMBL
Chdi Management/Chdi Foundation
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant full-length human FLAG-tagged ATM assessed as reduction in p53 S15 phosphorylation incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Chdi Management/Chdi Foundation
Curated by ChEMBL
Chdi Management/Chdi Foundation
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of ATM in human MCF7 cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 1 hr by ICW assayMore data for this Ligand-Target Pair