BDBM50550659 CHEMBL4763108

SMILES [H][C@@]12CN(CCOc3ccc4Sc5c(Cc4c3)cccc5-c3cc(=O)cc(o3)N3CCOCC3)[C@@]([H])(CO1)C2

InChI Key InChIKey=FMAIGHDZPIKVKX-ZJSXRUAMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50550659   

TargetSerine-protein kinase ATM(Homo sapiens (Human))
Chdi Management/Chdi Foundation

Curated by ChEMBL
LigandPNGBDBM50550659(CHEMBL4763108)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of recombinant full-length human FLAG-tagged ATM assessed as reduction in p53 S15 phosphorylation incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Chdi Management/Chdi Foundation

Curated by ChEMBL
LigandPNGBDBM50550659(CHEMBL4763108)
Affinity DataIC50:  210nMAssay Description:Inhibition of ATM in human MCF7 cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 1 hr by ICW assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed