BDBM50550662 CHEMBL4748079

SMILES FC1(F)CCN(CCOc2ccc3Sc4c(Cc3c2)cccc4-c2cc(=O)cc(o2)N2CCOCC2)C1

InChI Key InChIKey=GIBZWELVYXSKFQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50550662   

TargetSerine-protein kinase ATM(Homo sapiens (Human))
Chdi Management/Chdi Foundation

Curated by ChEMBL
LigandPNGBDBM50550662(CHEMBL4748079)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of recombinant full-length human FLAG-tagged ATM assessed as reduction in p53 S15 phosphorylation incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Chdi Management/Chdi Foundation

Curated by ChEMBL
LigandPNGBDBM50550662(CHEMBL4748079)
Affinity DataIC50:  260nMAssay Description:Inhibition of ATM in human MCF7 cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 1 hr by ICW assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed