BDBM50551131 CHEMBL4787257
SMILES Cc1ccc(NC(=O)c2ncn(CC(=O)NCc3ccc4c(N)nccc4c3)n2)cc1C
InChI Key InChIKey=DTGNUGZZTITRDZ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50551131
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University Of Michigan Medical School
Curated by ChEMBL
University Of Michigan Medical School
Curated by ChEMBL
Affinity DataIC50: 6.92E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
University Of Michigan Medical School
Curated by ChEMBL
University Of Michigan Medical School
Curated by ChEMBL
Affinity DataIC50: 2.16E+5nMAssay Description:Inhibition of recombinant human PRMT8 using histone H4 as substrate by hotspot assayMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 7(Homo sapiens (Human))
University Of Michigan Medical School
Curated by ChEMBL
University Of Michigan Medical School
Curated by ChEMBL
Affinity DataIC50: 6.94E+4nMAssay Description:Inhibition of recombinant human PRMT7 using GST-GAR as substrate by hotspot assayMore data for this Ligand-Target Pair