BDBM50551663 CHEMBL4779315

SMILES COc1cc2nccc(Oc3ccc(NC(=O)C(OC(=O)c4ccc(F)cc4)C(C)(C)C)cc3F)c2cc1OC

InChI Key InChIKey=FVPYEAORCOKOLV-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50551663   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50551663(CHEMBL4779315)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr) 4:1 as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50551663(CHEMBL4779315)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of c-Kit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50551663(CHEMBL4779315)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50551663(CHEMBL4779315)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50551663(CHEMBL4779315)
Affinity DataIC50:  295nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50551663(CHEMBL4779315)
Affinity DataIC50:  540nMAssay Description:Inhibition of Flt4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50551663(CHEMBL4779315)
Affinity DataIC50:  19nMAssay Description:Inhibition of Ron (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed