BDBM50552497 CHEMBL4763909

SMILES Cl.CCCCCCCCCCCCc1ccc(CN2CCC[C@@H]2CO)cc1

InChI Key InChIKey=CMBJZXOSIPCMEZ-GJFSDDNBSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50552497   

TargetSphingosine kinase 1(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50552497(CHEMBL4763909)
Affinity DataKi:  679nMAssay Description:Inhibition of recombinant human SphK1 expressed in baculovirus infected Sf9 cells assessed as decrease in [33P]SIP production using D-erythro-sphingo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50552497(CHEMBL4763909)
Affinity DataKi:  951nMAssay Description:Inhibition of recombinant human SphK2 assessed as decrease in [33P]SIP production using sphingosine as substrate in presence of [gamma33P]-ATP by sci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50552497(CHEMBL4763909)
Affinity DataEC50:  154nMAssay Description:Inhibition of human SphK1 expressed in Saccharomyces cerevisiae KYA1 assessed as yeast growth at 30 degreeC measured after 24 to 48 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50552497(CHEMBL4763909)
Affinity DataEC50:  290nMAssay Description:Inhibition of human SphK2 expressed in Saccharomyces cerevisiae KYA1 assessed as yeast growth at 30 degreeC measured after 24 to 48 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed