BDBM50553014 CHEMBL4793698
SMILES CC(C)C(\C=C1/NC(=O)NC1=O)c1ccc([nH]c1=O)-c1ccc2cccc(F)c2c1
InChI Key InChIKey=YIOOYTASCMSTFZ-JAIQZWGSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50553014
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:Displacement of [3H]-PGE2 from human EP3 expressed in Chem-1 cell membranes incubated for 2 hrs by TopCount scintillation plate reader analysisMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Antagonist activity at human EP3 expressed in CHO cells assessed as suppression of sulprostone-induced inhibition of forskolin induced cAMP productio...More data for this Ligand-Target Pair