BDBM50553044 CHEMBL4750762
SMILES CCn1nc(C)c2ccc(cc12)-c1ccc(c(=O)[nH]1)C(CC)(CC)\C=C1/OC(=O)NC1=O
InChI Key InChIKey=QCOMAWPTCWCPBV-MOSHPQCFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50553044
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataKi: 270nMAssay Description:Displacement of [3H]-PGE2 from human EP3 expressed in Chem-1 cell membranes incubated for 2 hrs by TopCount scintillation plate reader analysisMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Antagonist activity at human EP3 expressed in CHO cells assessed as suppression of sulprostone-induced inhibition of forskolin induced cAMP productio...More data for this Ligand-Target Pair