BDBM50553047 CHEMBL4784483
SMILES CC(C)[C@H](\C=C1/OC(=O)NC1=O)c1ccc([nH]c1=O)-c1ccc2cccc(F)c2c1
InChI Key InChIKey=LJHNDLRPPVVCJF-VBNMEBLOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50553047
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]-PGE2 from human EP3 expressed in Chem-1 cell membranes incubated for 2 hrs by TopCount scintillation plate reader analysisMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human EP3 expressed in CHO cells assessed as suppression of sulprostone-induced inhibition of forskolin induced cAMP productio...More data for this Ligand-Target Pair