BDBM50553096 CHEMBL4787513

SMILES N[C@H]1CCNC(=O)CC[C@H](NC(=O)C[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)NCc1ccccc1CC(O)=O

InChI Key InChIKey=QXXQYOLAIXPCDN-PMVMPFDFSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50553096   

TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50553096(CHEMBL4787513)
Affinity DataKi:  887nMAssay Description:Binding affinity to recombinant full length human IRAP expressed in HEK293T cells using Leu-MCA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50553096(CHEMBL4787513)
Affinity DataIC50:  1.46E+3nMAssay Description:Inhibition of recombinant full length human IRAP expressed in HEK293T cells assessed as substrate cleavage using Leu-MCA as substrate by fluorogenic ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed