BDBM50554924 CHEMBL4746394::US20240059655, Compound PW0896

SMILES COc1cc(Cc2cc(ncn2)N2CCc3c2cccc3C(=O)NCCO)cc(OC)c1

InChI Key InChIKey=DNNVKCBIPFYJNY-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50554924   

TargetG-protein coupled receptor 52(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50554924(CHEMBL4746394 | US20240059655, Compound PW0896)
Affinity DataEC50:  850nMAssay Description:Agonist activity at human GPR52 expressed in HEK293 cells assessed as increase in cAMP levels incubated for 15 mins by Glosensor cAMP assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 52(Mus musculus)
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM50554924(CHEMBL4746394 | US20240059655, Compound PW0896)
Affinity DataEC50:  850nMAssay Description:In Vitro Evaluation of GPR52 Activation. Newly synthesized compounds were evaluated in a twelve-point concentration-response for GPR52 agonist activi...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetG-protein coupled receptor 52(Mus musculus)
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM50554924(CHEMBL4746394 | US20240059655, Compound PW0896)
Affinity DataEC50:  850nMAssay Description:In Vitro Evaluation of GPR52 Activation. Newly synthesized compounds were evaluated in a twelve-point concentration-response for GPR52 agonist activi...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent