BDBM50554937 CHEMBL4780654::US20240059655, Compound PW0787
SMILES OCCNC(=O)c1cccc2N(CCc12)c1cc(Cc2cc(F)cc(c2)C(F)(F)F)ncn1
InChI Key InChIKey=OLNVWBLTVAPNME-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50554937
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
University Of Texas Medical Branch
Curated by ChEMBL
University Of Texas Medical Branch
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to 5-HT2C (unknown origin) assessed as inhibition of ligand bindingMore data for this Ligand-Target Pair
TargetG-protein coupled receptor 52(Mus musculus)
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataEC50: 135nMAssay Description:In Vitro Evaluation of GPR52 Activation. Newly synthesized compounds were evaluated in a twelve-point concentration-response for GPR52 agonist activi...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 52(Mus musculus)
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataEC50: 135nMAssay Description:In Vitro Evaluation of GPR52 Activation. Newly synthesized compounds were evaluated in a twelve-point concentration-response for GPR52 agonist activi...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 52(Homo sapiens (Human))
University Of Texas Medical Branch
Curated by ChEMBL
University Of Texas Medical Branch
Curated by ChEMBL
Affinity DataEC50: 135nMAssay Description:Agonist activity at human GPR52 expressed in HEK293 cells assessed as increase in cAMP levels incubated for 15 mins by Glosensor cAMP assayMore data for this Ligand-Target Pair