BDBM50555101 CHEMBL4778517

SMILES Cc1cc(CN)cc(C)c1-c1ncn(C)c1-c1ccnc2cc(F)ccc12

InChI Key InChIKey=WOAOENGFAAUUGT-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50555101   

TargetHistone-lysine N-methyltransferase NSD3(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL

LigandBDBM50555101(CHEMBL4778517)Copy SMILESCopy InChI

Affinity DataIC50:  200nMAssay Description:Inhibition of GST-tagged NSD3-PWWP1 domain (247 to 398 residues) (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDB

In DepthDetails PubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetHistone-lysine N-methyltransferase NSD3(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL

LigandBDBM50555101(CHEMBL4778517)Copy SMILESCopy InChI

Affinity DataKd:  170nMAssay Description:Binding affinity to NSD3 PWWP1 domain (263 to 398 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) by SPR methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDB

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI