BDBM50555257 CHEMBL4763464

SMILES C[C@@H](O)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1csc2ccccc12)NC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@H](CS)NC(=O)COCCOCCNC(=O)c1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc12)C(C)(C)S)C(C)(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(O)=O)C(C)(C)C

InChI Key InChIKey=ZTMMOBYAAOFOJA-QGAUDRBESA-N

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50555257   

TargetGolgi-associated PDZ and coiled-coil motif-containing protein(Homo sapiens)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50555257(CHEMBL4763464)
Affinity DataKd:  49nMAssay Description:Binding affinity to C-terminal His6 tagged CAL PDZ domain (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by fluorescence pola...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF2(Homo sapiens)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50555257(CHEMBL4763464)
Affinity DataKd:  2.82E+3nMAssay Description:Binding affinity to NHERF2 PDZ2 domain (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by fluorescence polarization based comp...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF2(Homo sapiens)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50555257(CHEMBL4763464)
Affinity DataKd:  560nMAssay Description:Binding affinity to NHERF2 PDZ1 domain (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by fluorescence polarization based comp...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50555257(CHEMBL4763464)
Affinity DataKd:  330nMAssay Description:Binding affinity to NHERF1 PDZ1 domain (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by fluorescence polarization based comp...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed