BDBM50556038 CHEMBL389014
SMILES [H][C@@]1(CC[C@@]2([H])\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C)[C@H](C)CCS(=N)(=O)c1ccccc1
InChI Key InChIKey=FANCTJAFZSYTIS-IQUVVAJASA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50556038
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Endotherm
Curated by ChEMBL
Endotherm
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of human CYP24A1 expressed in Chinese hamster V79 cells using [3H-1beta]-1alpha,25(OH)2D3 as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Homo sapiens (Human))
Endotherm
Curated by ChEMBL
Endotherm
Curated by ChEMBL
Affinity DataIC50: 554nMAssay Description:Inhibition of CYP27B in human SW900 cells using 3H-(23,24)-25-(OH)D3 as substrate incubated for 5 hrs by HPLC methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CYP27A1 (unknown origin) expressed in Chinese hamster V79 cells using 1alpha-(OH)D3 as substrate measured after 24 hrs by HPLC analysisMore data for this Ligand-Target Pair
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Endotherm
Curated by ChEMBL
Endotherm
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of human CYP24A1 expressed in Chinese hamster V79 cells using [3H-1beta]-1alpha,25(OH)2D3 as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair