BDBM50556159 CHEMBL4784247

SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCc1ccccc1O

InChI Key InChIKey=GHPUYKXSUPCAAC-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50556159   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza Universit£

Curated by ChEMBL
LigandPNGBDBM50556159(CHEMBL4784247)
Affinity DataKi:  28nMAssay Description:Binding affinity to wild type HIV-1 p66/p51 reverse transcriptase/nucleic acid/dTTP ternary complex using poly(rA)/oligo(dT) as templates in presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza Universit£

Curated by ChEMBL
LigandPNGBDBM50556159(CHEMBL4784247)
Affinity DataKi:  31nMAssay Description:Binding affinity to free form of wild type HIV-1 p66/p51 reverse transcriptase using poly(rA)/oligo(dT) as templates in presence of [3H]dTTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza Universit£

Curated by ChEMBL
LigandPNGBDBM50556159(CHEMBL4784247)
Affinity DataKi:  36nMAssay Description:Binding affinity to wild type HIV-1 p66/p51 reverse transcriptase/nucleic acid binary complex using poly(rA)/oligo(dT) as templates in presence of [3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza Universit£

Curated by ChEMBL
LigandPNGBDBM50556159(CHEMBL4784247)
Affinity DataIC50:  83nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of wild type recombinant HIV-1 His-tagged p66/p51 reverse transcriptase assessed as inhibition of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza Universit£

Curated by ChEMBL
LigandPNGBDBM50556159(CHEMBL4784247)
Affinity DataIC50:  73nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of recombinant HIV-1 p66/p51 reverse transcriptase K103N mutant assessed as inhibition of [3H]dTT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed