BDBM50556773 CHEMBL4745610

SMILES Clc1ccc(NC(=O)N(CCN2CCOCC2)c2ccc3nc(NC(=O)Cc4ccccc4)sc3c2)cc1

InChI Key InChIKey=ZLFNHZWFKGOWRN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50556773   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50556773(CHEMBL4745610)
Affinity DataKi:  4.80nMAssay Description:Mixed-type inhibition of recombinant human sEH using PHOME as substrate measured after 15 mins by fluorescence based Lineweaver-burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50556773(CHEMBL4745610)
Affinity DataIC50:  0.0820nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate measured after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed