BDBM50559060 CHEMBL4786787
SMILES CN1CCN(CC1)c1ccc(Nc2ncc3nc(Nc4ccccc4)n([C@@H]4CCN(C4)S(=O)(=O)C4CC4)c3n2)cc1
InChI Key InChIKey=RNEHWYIFHKBZAW-XMMPIXPASA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50559060
TargetEpidermal growth factor receptor(Homo sapiens (Human))
H. R. Patel Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
H. R. Patel Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
H. R. Patel Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
H. R. Patel Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of EGFR L858R/T790M/C797S (unknown origin) using Poly (Glu, Tyr) as substrate measured after 40 mins by kinase-glo assayMore data for this Ligand-Target Pair