BDBM50559517 Remogliflozin::Remogliflozin a

SMILES CC(C)Oc1ccc(Cc2c(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)nn(C(C)C)c2C)cc1

InChI Key InChIKey=GSINGUMRKGRYJP-VZWAGXQNSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50559517   

TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Toho University

Curated by ChEMBL
LigandPNGBDBM50559517(Remogliflozin | Remogliflozin a)
Affinity DataIC50:  18nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Toho University

Curated by ChEMBL
LigandPNGBDBM50559517(Remogliflozin | Remogliflozin a)
Affinity DataIC50:  18nMAssay Description:Inhibition of human SGLT2 expressed in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50559517(Remogliflozin | Remogliflozin a)
Affinity DataIC50:  1.66E+4nMAssay Description:Inhibition of human SGLT1 expressed in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50559517(Remogliflozin | Remogliflozin a)
Affinity DataIC50:  1.66E+4nMAssay Description:Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed