BDBM50559974 CHEMBL4790850

SMILES COC(=O)c1ccccc1OCc1nc2n(ncc2c(=O)[nH]1)-c1ccccc1

InChI Key InChIKey=OFDUSMVPGGANBN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50559974   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559974(CHEMBL4790850)
Affinity DataEC50:  10nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed