BDBM50560467 CHEMBL4788859

SMILES Cc1cc(-c2cnc3cc(ccn23)-c2ccc(cc2)N2CCNCC2)c2cc(F)ccc2n1

InChI Key InChIKey=AGMGRCAUAZCHPG-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50560467   

TargetActivin receptor type-1(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50560467(CHEMBL4788859)
Affinity DataIC50:  11nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50560467(CHEMBL4788859)
Affinity DataIC50:  166nMAssay Description:Inhibition of human ALK1 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50560467(CHEMBL4788859)
Affinity DataIC50: <5nMAssay Description:Inhibition of human ALK3 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetActivin receptor type-1B(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50560467(CHEMBL4788859)
Affinity DataIC50:  569nMAssay Description:Inhibition of human ALK4 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50560467(CHEMBL4788859)
Affinity DataIC50:  7.45E+3nMAssay Description:Inhibition of human PDGFRbeta using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50560467(CHEMBL4788859)
Affinity DataIC50:  29nMAssay Description:Inhibition of human ALK6 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein receptor type-2(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50560467(CHEMBL4788859)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human BMPR2 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-2(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50560467(CHEMBL4788859)
Affinity DataIC50:  587nMAssay Description:Inhibition of human TGFBR2 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50560467(CHEMBL4788859)
Affinity DataIC50:  1.34E+4nMAssay Description:Inhibition of human KDR using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50560467(CHEMBL4788859)
Affinity DataIC50:  1.27E+3nMAssay Description:Inhibition of human ALK5 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed