BDBM50560490 CHEMBL4749952

SMILES CC(C)C[C@H](NS(=O)(=O)c1cccc(c1)-c1ccc(F)cc1)C(=O)N[C@@H](Cc1ccccc1)C#N

InChI Key InChIKey=LSACLAVWRMJGMI-AHWVRZQESA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50560490   

TargetCathepsin K(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50560490(CHEMBL4749952)
Affinity DataKi:  134nMAssay Description:Inhibition of recombinant human cathepsin K expressed in insect cells using Z-Leu-Arg-AMC as substrate measured after 60 mins by fluorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50560490(CHEMBL4749952)
Affinity DataKi:  136nMAssay Description:Inhibition of recombinant human cathepsin S expressed in insect cells using Z-Phe-Arg-AMC as substrate measured after 60 mins by fluorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50560490(CHEMBL4749952)
Affinity DataKi:  5.56E+4nMAssay Description:Inhibition of human cathepsin B using Z-Arg-Arg-pNA as substrate measured after 60 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed